Equine Reproductive Research
Thank you for your interest in equine reproduction! One of the current focus areas in our laboratory is in field of molecular biology.
Specifically, we are looking at individual genes and their upward or downward expression in the uterus. We are using real-time quantitative PCR to measure gene expression.
We hope to develop a panel of different genes that would be indicative of different infertility problems. Using a common procedure to obtain uterine tissue (uterine biopsy), we hope to be able to tell owners about uterine function.
Currently, uterine cytology, culture and biopsy are used when a mare has a reproductive problem, but the information is rather crude and not very detailed.
By looking at specific genes, such as oxytocin, prostaglandin, interleukins and others, we may be able to arrive at a better diagnosis, prognosis and recommend more direct therapies.
Molecular studies can be costly. Many of the reagents we use are expensive and the tests need to be run in triplicate and validated with many horses. Contributions to this web site will directly affect our progress in this area. Your assistance is greatly appreciated. We will continue to post updates on our research on this page.
Current and Recent reproduction projects:
- Use of various frozen semen insemination methods and their effect on total semen deposited
- Gene expression in the mare’s uterus
- Formation of a diagnostic array for fertility in the mare
- The role of platelet activating factor in equine spermatozoa
Some of Dr. Dascanio’s research and case reports may be found on www.pubmed.gov. Other papers may be found on agricola.nal.usda.gov/.